NERVE BIOPSY

Sensory loss from whole sural nerve biopsy.

Discomfort after fascicular sural nerve biopsy.

Sural nerve biopsy may, in selected cases, give valuable information in the investigation of patients with polyneuropathy. The prevalence and severity of patient discomfort after fascicular nerve biopsy was investigated in 67 patients by a mailed questionnaire. A lasting (greater than 6 months) significant discomfort was found in 6 patients (11%), in 3 of these the symptoms were graded as sever...

Indications and usefulness of nerve biopsy.

P rogress in neurophysiology and neurogenetics as well as previous neuropathological findings have all improved our knowledge of the pathophysiological characteristics of peripheral nerve disorders. Thanks to these improvements, the indications of nerve biopsy have decreased during the past decade, making this invasive procedure unnecessary in the vast majority of patients with peripheral neuro...

Sequelae following sural nerve biopsy in type 1 diabetic subjects.

OBJECTIVES To detect post-operative sequelae of sural nerve biopsy. MATERIALS AND METHODS A questionnaire mailed to type 1 diabetic patients (n = 24; male/female 23/1; reply n = 23) 2 years after biopsy. RESULTS Type 1 diabetic patients (age 56 [11]; median [interquartile range]) had a long duration of diabetes (DM; 20 [19] years) and all had neuropathy. Three out of 24 patients developed i...

Nerve biopsy and conduction studies in diabetic neuropathy.

Morphological findings in sural nerves were related to nerve conduction in 12 patients with diabetic neuropathy, five with mainly sensory involvement, four with severe, symmetrical sensory-motor polyneuropathy, and three with multiple mononeuropathy. All had loss of large and small myelinated and of unmyelinated fibres, even early in the disease; segmental remyelination was the most prominent m...